Vitamin K Im Injection Site Adults
For injection dosage form.
Vitamin k im injection site adults. Therefore vitamin k should be injected into a muscle or vein only when it cannot be given by injection under the skin or taken by mouth or when your doctor has judged that the benefit is greater. The initial recommended dose is 2 5 mg to 25 mg or more rarely up to 50 mg. Vitamin k1 injection phytonadione injectable emulsion usp aqueous dispersion of vitamin k1 for parenteral injection possesses the same type and degree of activity as does naturally occurring vitamin k which is necessary for the production via the liver of active prothrombin factor ii proconvertin factor vii plasma thromboplastin component factor ix and stuart factor factor x. Children use is not recommended.
Consider 2 5 5 mg po once. In blood plasma 90 of vitamin k 1 is bound to lipoproteins. A single injection of vitamin k for newborns is standard. Plus the body is good at recycling its existing.
Prophylaxis and therapy of hemorrhagic disease of the newborn when caused by deficiency or interference with vitamin k activity. For the treatment of hypoprothrombinemia due to other causes. May repeat if needed after 24 hr. Systemic availability following intramuscular administration is about 50 and elimination half life in plasma is approximately 1 5 3 hours.
Inr 10 no bleeding. Usual pediatric dose for vitamin k deficiency. 2008 accp guidelines suggest 2 5 5 mg po once. For problems with blood clotting or increased bleeding.
Vitamin k deficiency is rare in adults because many of the foods we eat contain adequate amounts of k1 and because the body makes k2 on its own. Adults and teenagers the usual dose is 2 5 to 25 milligrams mg rarely up to 50 mg. For the treatment of anticoagulant induced prothrombin deficiency. 0 5 to 1 mg im once within one hour of birth use.
Following an intramuscular dose of 10 mg vitamin k plasma concentrations of 10 20 mcg l are produced normal range 0 4 1 2 mcg l. 2012 accp guidelines recommend vitamin k1 po dose not specified. While vitamin k deficiencies are rare in adults they are very common in newborn infants. The dose may be repeated if needed.
Minor bleeding any elevated inr. Oral vitamin k in adults. Vitamin k is also used to counteract an overdose. The initial recommended dose is 2 5 mg to 10 mg or up to 25 mg by mouth rarely 50 mg.
Usual pediatric dose for hypoprothrombinemia not associated with anticoagulant therapy.